Schwartz R., et al.
Prehospital Emergency Care. Vol. 15, No. 4. October/December 2011.
This study was conducted to compare the efficacy of ChitoGauze to Combat Gauze when controlling arterial hemorrhage in a swine model.
A femoral arterial injury was created using a 6-mm vascular punch, then allowed to free bleed for 45 seconds. Direct pressure was applied for 2 minutes with hemostatic agent. Although there were no statistically significant differences in the two study groups, and ChitoGauze and Combat Gauze were equally effective at achieving hemostasis, results noted the following:
- mean time to hemostasis was 13.1 minutes with ChitoGauze v. 32.4 minutes with Combat Gauze
- mean total blood loss was 774.6 ml for ChitoGauze and 1225.4 for Combat Gauze
ChitoGauze had trends toward superiority over Combat Gauze in all measured outcomes; however, these trends failed to reach statistical significance.
It is possible that these trends may become statistically significant with a larger sample size.